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Likelihood of amyloid formation in COVID-19-induced ARDS.

Sinha, Nabodita; Thakur, Ashwani K.

Trends Microbiol ; 29(11): 967-969, 2021 11.

Article in English | MEDLINE | ID: covidwho-1157751

ABSTRACT

Severe coronavirus disease 2019 (COVID-19) infection leads to multifactorial acute respiratory distress syndrome (ARDS), with little therapeutic success. The pathophysiology associated with ARDS or post-ARDS is not yet well understood. We hypothesize that amyloid formation occurring due to protein homeostasis disruption can be one of the complications associated with COVID-19-induced-ARDS.

Subject(s)

Amyloid/metabolism , COVID-19/complications , COVID-19/virology , Respiratory Distress Syndrome/etiology , Respiratory Distress Syndrome/metabolism , SARS-CoV-2 , Amyloidosis/etiology , Amyloidosis/metabolism , Amyloidosis/pathology , Animals , Disease Management , Disease Susceptibility , Humans , Respiratory Distress Syndrome/diagnosis

ABSTRACT

Subject(s)

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